Exploring early cardiac magnetic resonance features in acute myocardial infarction with bundle branch block

Objectives: To assess early cardiac magnetic resonance (CMR) features in patients with acute myocardial infarction (AMI) combined with bundle branch block (BBB).

Methods: The data of patients diagnosed with AMI and completing CMR within two weeks were included, and they were divided into the BBB group and the non-BBB group, and the acquired CMR images were post-processed by applying the CVI42 software, and the relevant CMR parameters, such as the left ventricular function, the myocardial strain (MS) and the late gadolinium enhancement (LGE), were observed and compared, and the binary logistic regression model was used to analyze the independent effects of the parameters on the patients with AMI accompanied by BBB.

Results: A total of 57 patients with AMI who completed CMR within two weeks were included in this study, of whom 19 were with BBB and 38 were without BBB. In multifactorial analysis Left ventricular ejection fraction (LVEF) (OR: 0.885; 95% CI: 0.788 to 0.994; p=0.040), LGE area (OR:1.143; 95% CI: 1.006 to 1.298; p=0.040), LGE volume (OR. 1.271; 95% CI: 1.026 to 1.576; p=0.028) and global circumferential strain (GCS) (OR. 0.775; 95% CI: 0.602 to 0.998; p=0.048) were the independently influencing CMR parameters in patients with AMI with BBB.

Conclusions: CVI42 measurement of early CMR parameters such as LVEF, GCS, and the area and volume of the LGE better responds to the impact on patients with AMI with BBB and thus guides clinical treatment.

Keywords: Acute myocardial infarction; Bundle branch block; Cardiac magnetic resonance; Myocardial strain; late gadolinium enhancement